US public health officials are investigating 450 cases of vaping-related lung illness across 33 states and one USA territory.
No single device, ingredient or additive has been identified at this time, though NY health officials are probing vitamin E acetate as a potential cause of some of the illnesses.
Health and Human Services Secretary Alex Azar says the Food and Drug Administration will develop guidelines to remove all e-cigarette flavors from the market, especially those favored by children.
MI became the first state to ban flavored e-cigarettes earlier this month, while San Francisco in June took a step to curb teen vaping addiction by banning the sales of the devices. Agency officials instead said they were studying if flavors could help smokers quit traditional cigarettes.
"We simply have to remove these attractive flavored products from the marketplace until they can secure FDA approval, if they can", Azar said.
Medical experts believe e-cigarettes in flavors like mango, mint and fruit, appeal too much to children.
The decision comes amid outcry over the increase in teen vaping.
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And Trump said the e-cig companies can afford to contend with new roadblocks to the youth market. "We need to do all we can to protect the public from tobacco-related disease and death, and prevent e-cigarettes from becoming an on-ramp to nicotine addiction for a generation of youth".
Public health officials in Idaho have confirmed that two people in the state have developed a serious lung disease linked to vaping.
FILE - In this February 20, 2014, file photo, a patron exhales vapor from an e-cigarette at a store in NY.
Azar said it will be several weeks before his department releases its proposal to crack down on flavored e-cigarettes.
E-cigarette manufacturers have been trying to market their products as better alternatives to cigarettes.
E-cigarette vapor contains tiny particles that carry flavorings. But there is virtually no research on the long-term effects of vaping.