An autopsy to establish Erin's cause of death is pending.
An emergency 911 call was placed shortly after 4 p.m. Saturday, according to the sheriff, and Moran was found deceased in a small-town trailer park about 130 miles south of Indianapolis.
The sheriff's office in Harrison County, in southern in where Moran had been living, said Monday that a "joint investigation into Mrs. Moran's death was conducted".
Standard toxicology tests were performed and the results are pending, the statement said, but no illegal narcotics were found at Moran's residence.
"Such sad sad news", Ron Howard - who played her older brother, Richie - tweeted.
Moran had reportedly recently been made to leave her trailer park home in IN with her husband Steve Fleischmann and was living in a motel while battling substance abuse, according to United States media.
It was a welcome infusion of cash for Moran, who had only a handful of acting gigs in the last 25 years according to IMDb.com, and was said to be living in an in trailer park and struggling with personal issues.
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Baio and Moran began working together in the late 1970s when they starred as Charles "Chachi" Arcola and Joanie Cunningham, respectively, on the ABC sitcom Happy Days.
Joanie may love Chachi, but we don't!
As a child, Moran made guest appearances on shows including "My Three Sons" and "Family Affair".
Last July, Howard got emotional when he talked to ET about the loss of his mentor, the late Garry Marshall, who created Happy Days.
Her body was found Saturday in a home in southern Indiana. She truly cared about others first, a true angel. She had also been said to have problems with heroin and alcohol, sparking speculation she died of an overdose. Again, I don't know if that's what killed her, I'm sure it was a culmination of years and years of doing it that might have had something to do with it.
That's so sweet. Henry Winkler, who played the Fonz, wrote, "OH Erin... now you will finally have the peace you wanted so badly here on earth ..." She did enjoy small roles in films like Dickie Roberts: Former Child Star and Not Another B Movie, but was largely absent from the Hollywood scene in the 2010s.
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