"They typically do get strong systems this time of the year in that part of the country, but this one is may be a notch stronger than what you typically see", said meteorologist Marc Chenard of the weather service's Weather Prediction Center in College Park, Maryland.
The storm will sweep right through the Rockies, the Upper Midwest, the central and northern Plains and more of the US heartland.
The National Weather Service posted a GIF on Wednesday showing the system shaping up.
A storm system that could generate severe weather in Alabama tomorrow is bringing "historic" blizzard conditions to parts of the Great Plains today, according to the National Weather Service.
All six runways at Denver International Airport were shut down, along with the main road into the airport due to drifting, blowing snow.
The storm triggered multiple accidents, making many Colorado roads and highways almost impenetrable.
Sexton warns Wales: Ireland have stopped winning runs before
Sexton said Best - who turns 37 in August - would be much missed when he retires from Test rugby after the World Cup. "We have got to be disciplined".
"'We are anticipating some possible delays and cancellations, be sure to check your flight status with your airline".
Travel may be impossible, CNN reports, and both flights and schools are being canceled in areas where the white-out blizzard may hit.
Many police departments across the state have sent out blizzard survival tips, urging people to carry emergency kits with them if they venture out into the formidable weather.
Additional snowfall from 2 p.m.to midnight will be more than 6 inches for Denver to Limon and Denver to Monument.
Heavy rain is expected Wednesday night through Thursday throughout the region, which may lead to flooding, AccuWeather says.
"The heavy snow and visibility near zero will create extremely unsafe travel conditions, and power outages are also possible", according to the weather service.
The National Weather Service Denver/Boulder said, "Blizzard conditions are likely across the northern mountains, northern foothills, Palmer Divide and adjacent plains".
Winter Storm Taylor has already spread snow and gusty winds from coast to coast across the northern tier of the U.S.in early March. CBS Denver reporter Jamie Leary documented how the wind almost blew her - as well as her selfie stick - away when she exited her news van.