Wintry weather bedeviled Thanksgiving weekend travelers across the United States on Saturday as a powerful and risky storm moved eastward, dumping heavy snow from parts of California to the northern Midwest and inundating other areas with rain.
NWS said that traveling during the storm could become "impossible" due to the snow and ice expected.
The winter storm is also bedeviling motorists around the U.S.as it dumps heavy snow from parts of California to the northern Midwest and drenches other areas with rain.
Aaron Reynolds, a meteorologist with the National Weather Service in Buffalo said the precipitation earlier on Sunday morning is "coming in, in the form of freezing rain, but as it runs into some colder air, it's going to turn over to snow and then some sleet mixed in with it too, especially as we go on, progress through the day".
The storm was hitting much of the central USA with blizzard conditions as of Saturday afternoon before it will make its way to the Northeast by Sunday. It is likely this region will see at least 1-3 inches of snow on Sunday into Monday, and possibly 6 inches or more in far Northwestern NJ.
NPR says that according to FlightAware, more than 225 US flights had been canceled and more than 2,000 delayed on Saturday alone.
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Investigators from the NTSB have been dispatched to the scene in rural Brule County, agency spokesman Knudson said. The three injured were taken to a hospital in Sioux Falls but their conditions was not released.
Blizzard conditions early on Saturday were already buffeting the High Plains.
As of Saturday afternoon, nearly 600 flights had been canceled and more than 9,600 delayed in the U.S., according to FlightAware.
The unsafe snowstorm moved towards the country's north-east on Sunday, with hundreds of flight cancellations and delays affecting Thanksgiving travellers.
The Federal Aviation Administration said some flights heading to Newark, New Jersey, are being delayed by an average of more than 2 1/2 hours. The Lighthouse Parking Lot near the Duluth ship canal in Canal Park also was closed as of 4 p.m.as waves continued to build along the Lake Superior shore. Another system is forecast to develop in the mid-Atlantic Sunday, moving into a nor'easter by Monday.
All roads in and out of Casper were closed Saturday morning, including the entire 300-mile stretch (483-kilometer) of Interstate 25 in Wyoming. A mix of rain, sleet and snow is forecast to change over all snow on Saturday night.
The overnight snow also meant the University of Minnesota had to have crews clear the seats at TCF Bank Stadium ahead of Saturday's big college football game against Wisconsin.
Major highways reopened Sunday in Wyoming and Colorado, a day after blizzard conditions clogged roads with snow drifts.