Pressure mounted on Jeremy Corbyn to trigger a confidence vote in the Government, but shadow chancellor John McDonnell said his party would make such a move when "the time is right".
"Under any scenario, people are going to be poorer, people are going to lose their jobs".
"If not, we risk a break with the British tradition of moderate, mainstream politics that goes back to the Restoration in 1660".
"The prime minister's got to stop threatening parliament and indeed, threatening the whole of the United Kingdom, that it's a choice between her deal and no deal - that's not the case".
The SNP, along with the Liberal Democrats and the Greens has indicated its support for holding another referendum on leaving the European Union, a proposal also backed by several MPs from the Conservatives and Labour.
Mr Cable said this could be done by revoking Article 50, the mechanism which triggered the exit process, or by holding a second referendum.
"We've got to take responsibility, I think we've got to act in all our interests and that's what we will be doing".
"We know that for certain industries there will be very specific impacts on them in a negative way", he said.
Corbyn is seeking to topple the government by forcing a general election.
Gov. DeSantis Suspends Sheriff Israel
Soon after the February 14 mass shooting, Israel faced criticism about his agency's response, including calls for his resignation. Sheriff Israel repeatedly defended their actions and his own when asked about the failures by the investigating commission.
Writing in the Sunday Times, he said it is "time for the United Kingdom to call the shots", insisting there is still time to demand a zero-tariff trade deal from Brussels.
Mrs May now believes, Downing Street said, that "based on the evidence of the last week", MPs managing to block Brexit is more likely than the United Kingdom leaving the European Union without a deal.
Transport Secretary Chris Grayling insisted the Government has put forward a "sensible compromise deal" before denying troops were being sought to help with no-deal Brexit traffic plans.
On Monday the debate on the meaningful vote on Mrs May's deal will resume for a fourth day.
The vote had been scheduled to take place in December but was called off at the 11th hour with Government victory looking unlikely.
In other reports on Sunday, it was revealed that Bercow had met with arch Remainer Dominic Grieve before the Speaker breached Commons precedent by allowing Grieves' amendment on Wednesday in attempts to derail a WTO Brexit.
The EU is waiting to see the outcome of Tuesday's vote - and the margin of the expected defeat - before considering its response, officials said, with some predicting that May will have to delay Brexit. But asked about a Brexit Plan B, Barclay hinted that May is not ready to ditch her plan if it's defeated, saying he "strongly suspects" lawmakers will end up voting for "something along the lines" of the current deal.
He told Marr: "Clearly if Theresa May's deal is voted down, clearly if a general election takes place and a Labour government comes in - an election would take place February, March time - clearly there's only a few weeks between that and the leave date, there would have to be time for those negotiations".