Denver, Seattle, Boise, Dallas, Los Angeles, Chicago, and Phoenix were some of the cities to have confirmed issues with internet, television, phone, and home security services, Scripps station KIVI reported.
At about 3 p.m., CenturyLink tweeted it had "made progress in restoring services across the network in the last several hours" but was "focused on resolving remaining issues".
CenturyLink expects the service to be restored within hours.
Customers from NY to California reported outages.
The county's 311 service appeared to be unaffected, the agency said, and its 911 text message service also still functions.
CRESA is the Clark County Regional Emergency Services Agency, charged with providing 911 services for the area.
A nationwide outage involving an internet company affected 911 cell phone calls in MA early Friday morning, according to State Police.
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Due to sporadic 911 outages in MA, public safety officials recommended individuals looking for emergency help use the 10-digit telephone number of the fire or police departments they wanted to contact.
Originally published December 27 at 1:47 p.m. PT. Most recent update, December 28 at 9:09 a.m. PT: Adds company comment about progress toward restoring service and Ajit Pai's comment.
"We apologize for the inconvenience w/ multiple alerts", CRESA tweeted.
The effect on people's ability to reach 911 emergency services is "completely unacceptable", he said. But the company says it does not yet know the extent of service outages. It provided no other details, including how many customers were affected.
On Friday, the website reported similar outages in many areas.
The problem caused business disruptions in eastern Idaho and 911 emergency services were reportedly affected in other parts of America.