After a solid start from Lacko, the breakthrough came in the seventh game of the opening set.
The Frenchman has never been beyond that stage and to do so will have to defeat 11th-seeded Querrey.
Top-ranked Rafael Nadal is also back in the quarterfinals for the first time since 2011.
He hasn't dropped serve since last year's semifinals, per The Guardian.
Roger Federer and Serena Williams will be expected to maintain their flawless progress at Wimbledon as the title favourites head into the fourth round looking to survive the tournament's giant-killing carnage on Monday.
And it's got everything to do with the World Cup.
World number two Federer, eyeing a 21st Grand Slam title, has won all five of his previous meetings with Mannarino, a 30-year-old journeyman who has never been past the last 16 at a major.
The No. 9 seed, at 38 the oldest woman in the draw, came back to beat 141st-ranked qualifier Alexandra Dulgheru of Romania 4-6, 6-0, 6-1 to reach the third round at the All England Club.
Cibulkova did just that, regaining her composure to break and take the first set, before comfortably closing out victory in the second.
But the American, the runner-up at Wimbledon a year ago, then won seven games in a row.
Not for the first time at Wimbledon, Dominika Cibulkova was left agitated by a decision that went against her.
Wozniacki is still waiting to get past the round of 16 for the first time, despite fighting back from 5-1 down in the third set and saving four match points at 5-3. It's also a first for any Grand Slam tournament in the 50-year professional era.
Isner, 33, will be playing in his first quarter-final at the majors since the 2011 US Open when he faces former Wimbledon finalist Milos Raonic.
Trump Zeros in on Supreme Court Pick
The judge had to meet with the Senate Judiciary Committee twice but was appointed to the court in 2016. Kethledge has some political experience having worked on Capitol Hill as an aide to former Sen.
After seven minutes, the decision was finally changed and the point replayed.
Romanian 29th seed Mihaela Buzarnescu thrashed British teenager Katie Swan, 6-0, 6-3 to extend her remarkable renaissance.
The 2016 runner-up won 7-6 (4), 7-6 (4), 7-6 (4) in a match that only featured one break of serve for each player in the second set.
Anderson is the first South African man in the Wimbledon last-eight since Wayne Ferreira in 1994. "After that, I feel like I got, how do you say, there is a buzz for me". "That's absolutely fine. It's obviously a marketing coup for Roger".
So what, Federer was asked, makes him so successful on grass?
Mihaela Buzarnescu of Romania has become the first player to book a place in the third round of Wimbledon.
The 12th-seeded Ostapenko was aggressive throughout, hitting 28 winners - 13 coming off her backhand. She was joined in the third round minutes later by 10th-seeded Madison Keys of the United States, who dispatched Luksika Kumkhum of Thailand 6-4, 6-3.
Here is a look at talking points generated across six days at the All England Club.
The 13th-seeded Raonic was playing John Millman of Australia as he bids to reach the third round for a sixth straight year. It was her 16th straight victory at Wimbledon, although she missed last year's tournament while pregnant.
Roger Federer and Serena Williams were both set to play on Centre Court later.
She returned to the All England Club stuck in a rut after losing in the first round of both the Australian and French Opens this year.
Williams was almost as good, losing just five of 32 points on her first serve in a 6-1, 6-4 win over Viktoriya Tomova.
Not one top-10 seed has made the women's quarterfinals at Wimbledon.