Israel's violent crackdown on the protesters has drawn widespread criticism, with Kuwait urging a meeting of the UN Security Council to discuss the situation along the Gaza-Israel border.
The Minister of State for Foreign Affairs indicated, "Jerusalem is a special spiritual value for the humans and as our hearts strive for it every day, we call on the global community to shoulder its responsibilities to stop violence against the fraternal Palestinian people, halt the vicious attack against it and end the brutal occupation".
"We call for a credible worldwide investigation into the crimes committed by the occupation", Abul Gheit said at the opening session of an extraordinary meeting of Arab foreign ministers in Cairo to discuss the violence.
"The Arab summit last month [in Saudi Arabia] declared its rejection, in accordance with worldwide law, of any move that attempts to legitimise any decision that changes the status of Jerusalem", Shoukry said.
Israel said Wednesday that Palestinian protests on the Gaza-Israel border have dropped off dramatically, citing what it said were Egyptian efforts to restore calm.
It also said that the current US President Donald Trump administration's unconditional support to Israel surpasses that of its predecessors and isolates the US at the global level.
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The United Nations will continue to support Israelis and Palestinians on the road to peace by helping them to take the historic steps to achieve a solution of two States living side by side in peace and within secure and recognized borders, with Jerusalem as the capital of both.
The unacceptable violence and incitement exacerbate mistrust between Palestinians and Israelis. Palestinian security sources confirmed the target was a Hamas base, saying there were no reports of injuries.
Israel, which has faced blistering global criticism over its response, is likely to latch on to the remarks to bolster its claims that Hamas has used the weekly border protests as cover to stage attacks.
It spotlighted the Higher National Commission for the Great March of Return calling on Palestinians to partake in today's protests, dubbed "Friday of Honoring the Martyrs", and affirming the peaceful nature of the protests. "Canada calls for an immediate independent investigation to thoroughly examine the facts on the ground - including any incitement, violence, and the excessive use of force".
Israel accuses Hamas, with whom it has fought three wars since 2008, of seeking to use the demonstrations as cover for violence. Some of the Palestinians at the border, including terrorist operatives, attacked Israeli soldiers with Molotov cocktails and other weapons as they attempted to breach the border fence.