"Bush, now age 92, has decided not to seek additional medical treatment and will instead focus on comfort care", McGrath said.
Bush is also the mother of George W. Bush, who served as president from 2001 until 2009, and Jeb Bush, the former governor of Florida who ran for president in 2016.
Most recently, she was admitted to Houston Methodist Hospital on Good Friday suffering from shortness of breath. Jim McGrath, who issued a statement, said that she is surrounded by a familyand appreciates the messages and prayers she's been receiving from people.
Rep. Sean Maloney, D-N.Y., paid tribute to Bush as "a graceful First Lady who has dedicated her life to improving education and promoting literacy", while Maryland Gov. Larry Hogan called her "an incredible First Lady and a great American". Barbara Bush eschewed dying her hair, which ultimately turned white. She had heart surgery in 2009, and was operated on for an ulcer the year before.
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Husband George, the nation's 41st president, is now 93 years old and struggling with a Parkinson's-like disease that forces him to use a wheelchair and makes it hard for him to speak. They married in 1945 while he was on leave from wartime service as a naval officer.
She was known for her trademark white hair, a trait that was born of tragedy when her brown hair began to gray in the 1950s, while her 3-year-old daughter Pauline, known to her family as Robin, underwent treatment for leukemia and eventually died in October 1953, according to the Associated Press.
Bush is the only living wife of one former President and the mother of another former President. Her father was the publisher of McCall's and Redbook magazines.
Barbara Pierce Bush was born in Rye, New York. The foundation partners with local programs and had awarded more than $40 million as of 2014 to create or expand more than 1,500 literacy programs nationwide.