By contrast, other vascular conditions and diseases - such as deep venous thrombosis, pulmonary embolism and peripheral artery disease - are thought to be serious and risky.
What's more, they were twice as prone to build up an aspiratory embolism - a clot which goes into the lungs and can be destructive.
If you are living with varicose veins and they're becoming increasingly painful, it's best to speak to a health professional to see what treatment options are available.
They included: 'Regardless of whether the relationship between varicose veins and DVT is causal or speaks to a typical arrangement of hazard factors requires additionally research'. It's unclear whether varicose veins might cause blood clots, or whether the two share a similar cause.
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Response: Varicose veins are common, with about 23 percent of US adults having the condition, but they are rarely thought to be associated with serious health risks.
The study used claims data from the Taiwanese National Health Insurance program linked to the National Register of Deaths, to propensity-score match 212,984 patients diagnosed with varicose veins to a paired control group. Varicose veins can also happen during pregnancy, when hormonal and circulatory changes may bring about enlarged veins in the legs.
"Patients with varicose veins have increased incidence of inflammatory and prothrombotic markers", the researchers wrote.
The study results are not entirely new, Piazza said, since several studies have demonstrated an association between varicose veins and blood clots. Researchers tracked more than 200,000 patients and said more studies are needed. Animal models have shown higher concentrations of macrophages, monocytes, neutrophils, lymphocytes, and matrix metalloproteinases in venous valves exposed to high pressure for prolonged periods, like in varicose veins.