"I know there will be tough times ahead, and I try not to get too over-confident, but I've played quite a bit for England now and the experience has allowed me stay focussed on what's to come". However, the captain Jason Holder has confirmed the fitness of Gayle and said that he is ready and raring to go. Joe Root was dismissed soon after that and Chris Woakes joined Ali in the middle.
Ali s six-hitting assault really got going as England scored a remarkable 50 runs in two overs - the 45 and 46th of their innings.
He eventually holed out off spinner Ashley Nurse and received a standing ovation from a near-capacity crowd.
Following a washed-out second ODI at Nottingham's Trent Bridge on Thursday, Stuart Law's men only have three more matches in England - starting with Sunday's fixture in Bristol - and a three-match ODI series in New Zealand scheduled before the qualifiers.
Moeen Ali produced what has to be one of the most imperious batting displays so far in the year.
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In the other matches on Saturday, Burnley drew goalless with Huddersfield , while Watford secured a 2-1 win over Swansea City. Download the Nigeria Today app from Play store.
Meanwhile West Indies captain Jason Holder was left to lament his side s inability to build on a promising start, their cause not aided by some sloppy fielding as they suffered a 14th defeat in 15 completed ODIs against England.
Only 2.2 overs were possible after West Indies won the toss and elected to field first.
Plunkett then had both Shai Hope (20) and Marlon Samuels (11) caught behind, the latter on a tight review.
Gayle gave Moeen a dose of his own medicine by easing him for three consecutive sixes to move into the 90s, but was run out by a direct hit from Rashid as he casually ambled through for a single.
Moeen, who hit eight sixes, set a world record by taking only 12 deliveries after passing 50 to bring up his third ODI hundred, helping England to a mammoth 369-9. Bristol is not a happy hunting ground for West Indies; they are yet to register a win in three matches.