Republicans - including President Donald Trump - have professed their glee that she's still minority leader.
Ms Handel comfortably won the seat vacated by health and human services secretary Tom Price in the sixth congressional district of Georgia, beating Democratic candidate Jon Ossoff.
But it could give Republicans a boost in confidence as they struggle to advance health and tax legislation bogged down by infighting and investigations into whether Mr Trump's campaign colluded with Russian Federation in last year's presidential election.
The race for the 6th - a district made up of northern Atlanta suburbs - turned into the most expensive House race in history, with more than $50 million spent by both parties and super PACs.
But as Democrats are eager to point out, there are many more districts _ anywhere from 71 to 94, depending on how it's calculated _ that are more competitive than Georgia's 6th District.
Democrats invested millions in the costliest House race, but Republican Karen Handel beat Jon Ossoff on Tuesday. "We clearly need to have the right message and the right messengers to show the American people that we can help and that we have a vision, that we have a plan".
Several prominent Democrats said the party needed to rethink its approach heading into next year's congressional elections, when Democrats need to pick up 24 seats to regain control of the House of Representatives.
Charter roadshow off to chaotic start as Zwane flees imbizo
On Wednesday, global rating agency Moody's warned that the charter is harmful to the South African economy. The announcement of the new Mining Charter by Zwane last week sent the rand and mining shares diving.
"We as Democrats have to come to terms with the fact that we lost again", said Rep. Seth Moulton, D-Mass.
House Democratic leader Nancy Pelosi says she's confident she has the support in her caucus despite finger-pointing and frustration after Democrats lost a Georgia special election.
Rep. Tim Ryan, an Ohio Democrat who unsuccessfully challenged Pelosi for speaker, told the New York Times that Pelosi's toxicity among the electorate is a "problem". I am a strategic, politically astute leader. "This race proved that Democrats have a real shot at taking back the House in 2018". Republican voters have peeled away in alarming numbers in all four races, perhaps because they see a Congress pushing an unpopular health care bill and showing a consistent unwillingness to stand up to a risky president.
Trump was quick to celebrate the Georgia win and accused Democrats of standing in the way of a legislative agenda bogged down by infighting and investigations into whether his campaign colluded with Russian Federation in last year's presidential election.
"I hope they keep Nancy for 10 more years".
"And don't forget, this happened in Montana, in Kansas", he added. The sooner the GOP can confirm conservative judges, pass tax relief and reform, replace Obamacare, and pass a budget that shores up the military while meaningfully restraining federal domestic spending, the better the chances they'll extend their winning streak into 2018. The GOP should remember this, too: Democrats won the first seven special elections after Barack Obama was elected in 2008, but the midterm elections in 2010 were disastrous for the party. Democrats have been overperforming in those races by historical margins. He has argued that Democrats should avoid engaging in identity politics and instead focus on issues affecting the middle class.
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