It was the second PGA Tour victory for 24-year-old Berger, who joins Dave Hill, Lee Trevino and David Toms as back-to-back winners in Memphis.
South Africa's Schwartzel had five birdies and a bogey in his four-under par 66 while Colombia's Muñoz carded a 67 that featured four birdies and a bogey.
Daniel Berger on the 18th green after winning during the final round of the FedEX St. Jude Classic at the TPC Southwind on June 11, 2017 in Memphis, Tennessee.
Billy Horschel, Rafa Cabrera Bello, Kevin Chappell, Chez Reavie and amateur Braden Thornberry tied for fourth at 8 under.
Stewart Cink is a shot back on eight-under with Ben Crane a further shot behind.
ATZENBRUGG, Austria - Chilean golfer Felipe Aguilar shot a 7-under 65 to build a two-stroke lead over a group of three on a sunny opening day of the Lyoness Open on Thursday.
Both of Berger's PGA Tour wins have come at TPC Southwind, where he finished 13 under en route to a three-shot victory a year ago.
South African Charl Schwartzel and Whee Kim of South Korea were a shot behind.
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"The good news is that my physical game is there and I should be able to find the mental toughness here soon", Mickelson said.
Jutanugarn finished with a three-under 69 in the final round and was tied with Thompson (72) and Chun (70) at 17-under 271.
Schwartzel grabbed the outright lead by picking up a shot at the second and missed a putt from six feet to double his advantage at the next, before bogeying his penultimate hole. Perrine Delacour (62) of France and American Lindy Duncan (65) were one shot back.
Jobe shot a 69 in the final round at the Wakonda Club to snap a winless drought that had stretched back to 1998, when he took first in a tournament in Japan.
Munoz, who made a late charge up the leaderboard in the first round, kept himself there with his second strong round, shooting four birdies to offset his first bogey of the tournament, which came on the par-4 18th.
Marco Dawson and Stephen Ames finished at 207.
He will tee it up in his third US Open on the back of a strong season, with four top-10 finishes and five top-25 finishes.
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