United went 14 games without defeat at the Lane before last season's 3-0 loss, but gone are the days when their former manager Alex Ferguson could dismiss Spurs' threat with a disdainful: "Lads, it's Tottenham".
Their Champions League hopes went up in smoke last season after they lost 3-2 to West Ham United in the final game at Upton Park.
Chelsea were crowned champions after their win at West Bromwich Albion on Friday, but Tottenham had the ideal occasion to forget that frustration as they prepare to temporarily play at Wembley while the Lane is demolished to make way for a new arena.
The 22-year-old took to Twitter on Tuesday afternoon to post an image in which he is pictured alongside Spurs teammate Ben Davies in the aftermath of Sunday's finale 2-1 win against Manchester United before the bulldozers moved in at the historic venue. It's a great moment to share with everyone, we're so happy to be here to say goodbye to White Hart Lane and to welcome the new stadium.
"We were talking a lot and we believe that when the new stadium opens the doors, it will help the club to reach the last level", Pochettino, whose side racked up a 14th consecutive home league win, said on Sunday (NZT Monday).
The England striker was mobbed by fans at the final whistle before returning to the pitch with his family for the ceremony and tradition end-of-season lap of honour.
"I wanted to try and get that victor as well, and for it to happen is just a dream come true".
Philippines bans smoking in public places, Twitter reacts with joy
About 23.8 percent of the adult population smoked in 2015, down from 28.3 percent in 2009, according to government surveys. Minors will also be prohibited from smoking, selling and buying cigarettes and other tobacco products, the EO says.
"We have a very bright future, with a team and squad who are hungry to learn, win and get better".
Not even 24 hours on from hosting its final game, the demolition team have moved quickly at White Hart Lane.
"We've got to use this as motivation to get there".
"I think we had 30-odd thousand throughout the whole season, we're going to have 80-odd thousand next year so we've got to make that a fortress as well".
"We have a special bond at Tottenham that you don't always get elsewhere".
Spurs, whose new stadium is still being built just around the corner, gave their home since 1899 a great farewell by beating José Mourinho's men 2-1, and will play all of their home games next season at Wembley.
Dan is ESPN FC's Tottenham correspondent.