In-form Valencia was rested for Sunday's 2-0 win at Burnley, where Pogba had to leave the field late on and was replaced by Michael Carrick. "It means nothing. If we finish fifth and they finish sixth and we are above them it means nothing", he added.
But the pair have not responded as their manager would have wished and remain sidelined for a game that sees Mourinho renew his fierce rivalry with City manager Pep Guardiola.
Manchester United manager Jose Mourinho has received criticism from some quarters for his use of Rashford this season.
Ibrahimovic has stalled over an extension on his current deal and his career will be assessed once his situation has been updated, as he's set to undergo surgery in America.
"Maybe they look at us with different eyes but I think they are not stupid, they are not naive, and they know that we are going to give them a fight".
"We think he is in fabulous hands and he has to recover from the injury and prepare himself mentally for the next step".
When pressed about the Swede's future, Mourinho replied: "I don't know, I don't want to know, I am not interested in it". Sergio is much better.
Here's the full list of injuries for the Manchester Derby.
Axelrod: It takes a lot of work to lose to Trump
At a forum in NY on Tuesday, Clinton said Comey's letter to Congress on October 28 was a factor in her loss to President Trump. But he said the only other choice, "concealment", would have been "catastrophic".
Yet, asked if that was a calculated risk, Mourinho said on Tuesday: "I don't care".
His goal against Sunderland earlier this month ended a scoring drought in the Premier League that stretched back to September.
"And we have Axel (Tuanzebe) waiting for an opportunity, we have (Timothy Fosu) Mensah, that in the (Netherlands) under-21 national team played as a central defender".
He said: "We should analyse game by game what happened".
Manchester United captain Wayne Rooney insists he has years left at the top level of football and is determined to prove his critics wrong in the closing weeks of the season. We arrived more and didn't score (in other games).
"Psychologically, it is not (important)".
"That is the most important thing".
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